Diels-Alder reactivities of cycloalkenediones with tetrazine
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چکیده
منابع مشابه
Appendix 1. Diels-Alder Reactions
One of the most efficient methods (high yield, controlled stereochemistry, diverse functionality) to construct rings from smaller fragments is via cycloaddition reactions. The reverse reaction, namely splitting of a ring into smaller fragments is termed a cycloreversion reaction is also an important synthetic tool. (For example, in the present experiment it is the cracking of cyclopentadiene di...
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This review illustrates how water, as an environmentally friendly solvent, can have significant additional benefits when it is used as a solvent for the Diels–Alder reaction. The mechanism by which the unique properties of water enhance the rate and selectivity are discussed. Also, possibilities for the achievement of further increases in rate and enantioselectivity of aqueous Diels–Alder react...
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A Diels-Alder reaction between cyclopentadiene and a variety of ketenimines is reported. A copper(I)-bis(phosphine complex catalyzes the cycloaddition across the C═N bond of the ketenimine in a [4 + 2] reaction to give an enamine intermediate that is hydrolyzed upon purification to generate aminoketones.
متن کاملAsymmetric Catalysis of Diels–Alder Reaction
The Diels–Alder (DA) reaction (or diene synthesis) between a diene and a dienophile generates two s bonds stereoselectively and up to four chiral centers in a single step to afford six-membered cyclic compounds. This cycloaddition reaction named after Professor Otto Paul Hermann Diels (1876–1954) and his student Kurt Alder (1902–1958) was discovered in 1928 during studies on the reaction of b...
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The Diels-Alder reaction has often been used to construct polycyclic quinones from either benzoquinones or naphthoquinones.' This strategy has led to elegant syntheses of certain anthracyclines and also many other acetate-derived compounds. Several researchers, most notably Gesson and Brassard, have determined that the presence of a chlorine or bromine atom on the starting quinone framework per...
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ژورنال
عنوان ژورنال: Journal of Molecular Modeling
سال: 2019
ISSN: 1610-2940,0948-5023
DOI: 10.1007/s00894-018-3909-z